CMP substitutions preferentially inhibit polysialic acid synthesis
نویسندگان
چکیده
منابع مشابه
CMP substitutions preferentially inhibit polysialic acid synthesis.
It is widely reported that derivatives of sugar moieties can be used to metabolically label cell surface carbohydrates or inhibit a particular glycosylation. However, few studies address the effect of substitution of the cytidylmonophosphate (CMP) portion on sialyltransferase activities. Here we first synthesized 2'-O-methyl CMP and 5-methyl CMP and then asked if these CMP derivatives are recog...
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ژورنال
عنوان ژورنال: Glycobiology
سال: 2007
ISSN: 0959-6658,1460-2423
DOI: 10.1093/glycob/cwm132